ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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Bone Grafts And Nuclear Medicine: Review
Dr. Ersoy KEKİLLİ,a Dr. Cengiz YAĞMUR,a Dr. Kadir ERTEM,b Dr. Bilge TÜRK BİLENc
aNükleer Tıp, bOrtopedi ve Travmatoloji, cPlastik ve Rekonstrüktif Cerrahi AD, İnönü Üniversitesi Tıp Fakültesi, MALATYA
Bone grafts find application in multiple settings: joint fusion and reconstruction, bone infection and resection, prothesis complications, congenital malformation and cosmetic adjustments, cranio-maxillofacial reconstruction, as well as the treatment of various trauma injuries such as fractures resulting in delayed unions and non-unions. Bone grafts have often played the roles of scaffolds, bridges, spacers, defect fillers, and bone-loss replacements. There is a growing trend in bone graft usage today. The use of autolog bone grafts is widespread in Turkey. Nuclear medicine has proven to be a helpful adjunct in the determination of graft viability. In particular, the status of vascular anastomoses can be shown on bone scintigraphy short periods after cortical and pedicle bone grafts. With added knowledge of individual pathophysiology, the interpretation of scintigraphic results is greatly facilitated. Non-vascularized bone grafts improve with revascularisation and remineralisation. In cancellous autografts, the vascular response is much greater than in cortical grafts. The entire cancellous bed may be completely revascularized within approximately l to 2 weeks. Healing of vascularized bone grafts and pedicles is similar to the process manifested in fractures. Allograft bone simply provides calcium scaffolding and does not possess bone-growing cells or proteins. Previous studies utilizing bone scintigraphy have shown that allograft healing proceeds not unlike that of autografts, with the exception that revascularisation and remineralisation are delayed. The authors review the current literature on bone grafting procedures and discuss the possible applications of nuclear medicine in this setting.Keywords: Bone transplantation, radionuclide imaging, nuclear medicineTurkiye Klinikleri J Med Sci 2005, 25:261-279
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