ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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ORIGINAL RESEARCH ARTICLES |
Evaluation Of Central Venous Catheter-related Infections In Uremic Patients: Incidence, Pathogens And Patient Characteristics
Dr. M. Emin YILMAZ,a Dr. Ali Kemal KADİROĞLU,a Dr. İsmail Hamdi KARA,b Dr. Bünyamin IŞIKOĞLUa
aNefroloji BD, bAile Hekimliği AD, Dicle Üniversitesi Tıp Fakültesi, DİYARBAKIR
Objective: To determine the incidence of central venous catheter (CVC)-related infections, types of pathogenic microorganisms encountered, as well as to annotate the characteristics of patients undergoing catheterization in the nephrology clinic.
Material and Methods: CVCs were inserted in 106 consecutive patients hospitalized with uremia during the 2001 calendar year in the nephrology clinic at the hospital of the Medicine Faculty of Dicle University. The predisposing factors of each patient were recorded. The catheter lumen was washed with saline after every hemodialysis session and saline along with low-moleculer weight heparin (LMWH, enoxaparin, 2000U/ml) was injected into both catheter lumen. The catheter tip as well as a blood sample were cultured from patients suspected of catheter-related infection.
Results: A total of 122 transient CVCs were inserted in the 106 patients. Infectious signs were established in 22 patients (20.7%). Staphylococcus aureus was isolated in the catheter tip culture of eleven, coagulase-negative staphylococci in seven, and two cases each manifesting Escherichia coli and Pseudomonas aeroginosa. Blood culture was positive in five patients (22.7%). The microorganisms isolated from blood cultures were Staphylococcus aureus in three patients, Staphylococcus epidermidis in one patient and Pseudomonas aeroginosa in another. Septicemia developed as a complication of CVC-related bacteriemia in one patient, who subsequently succumbed. The incidence of CVC-related bacteriemia was established as 4.7/1000 catheter days and the mortality rate was 9/1000. The characteristics of patients who had CVC-related bacteriemia were: age 60 years old and over, male gender, duration of indwelling catheter longer than 21 days, more than one instance of catheter use, anemia and urinary tract infections.
Conclusion: The results of our study were similar to those seen in reference studies. Staphylococcus aureus and coagulase-negative staphylococcus were the most prevalent pathogens isolated in blood and catheter tip cultures.Keywords: Catheterization, central venous, bacterial infections, agedTurkiye Klinikleri J Med Sci 2005, 25:183-189
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