ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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Benign Nodular Calcification Associated With Secondary Hyperparathyroidism Due To Renal Failure
Dr.Nurhan KOCAAYAN,a Dr.A. Tülin MANSUR,a Dr.Fatih GÖKTAY,a
Dr.Şirin PEKCAN,a Dr.Serkan TOSUNb
aDermatoloji Kliniği, bPatoloji Kliniği, Haydarpaşa Numune Eğitim ve Araştırma Hastanesi, İSTANBUL
Calcinosis cutis is characterized by deposition of calcium salts in the skin and subcutaneous tissue. Cutaneous calcification is divided into four forms: dystrophic, metastatic, iatrogenic and idiopathic.
A 58-year-old woman was admitted to our dermatology outpatient clinic with complaints of a 2-month history of a painful, white and firm nodular lesion over her right heel. Cutaneous sarcoidosis without systemic involvement had been diagnosed two years previously. Subsequently, end-stage renal failure requiring maintenance hemodialysis developed due to undefined nephropathy. During hemodialysis, serum biochemistry showed normal calcium but increased phosphorous and parathyroid hormon concentrations. X-ray showed globular heterogenous calcification located on the calcaneal fat pad. Histopathology revealed amorphous materials in the dermis with histiocytes and sparse multinuclear histiocytic giant cells surrounding them. As a result, benign nodular calcification was diagnosed and total excision of the lesion was performed.
In this report, we discuss the etiology and classification of metastatic calcinosis cutis and uremic tumoral calcinosis and review the current literature.Keywords: Benign nodular calcification, calcinosis cutis, metastatic calcification, uremic tumoral calcinosisTurkiye Klinikleri J Med Sci 2004, 24:416-420
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