ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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The Importance Of Iodine Deficiency In The Etiology Of Euthyroid Goiterin Patients From Different Geographical Parts Of Turkey
Murat Faik ERDOĞAN*, Nuri KAMEL**
* Uzm.Dr.Ankara Üniversitesi Tıp Fakültesi Endokrinoloji ve Metabolizma Hastalıkları BD,
** Prof.Dr.Ankara Üniversitesi Tıp Fakültesi Endokrinoloji ve Metabolizma Hastalıkları BD, ANKARA
Iodine deficiency is still considered to be the major etiological factor for endemic goiter. Although goiter has been the most significant clinical finding in iodine deficiency, a number of more important disorders have also been identified.
For the assessment of iodine deficiency in an endemic region, the detection of urinary iodine excretion in a sample group has been considered as a reliable method and has widely been used.
The aim of this study was to demonstrate the significance of iodine deficiencyt for endemic goitre in patients from different regions of Turkey.
Sixty patients and 20 controls were assased via thyroid function tests (TFT), urinary iodine concentrations and I131 uptake of thyroid glands. While TFT s were smilar in both groups, urinary iodine concentrations were significantly lower in patients’ group showing the lowest values in patients from the Eastern Blacksea region.
Seventy-six percent of our patients was found to have high I131 uptakes showing an inversely proportional relation with the urinary iodine concentrations, as would be expected.
In conclusion; iodine deficiency is still the major etiopatogenetic factor for endemic goiter in Turkey and this can easily be detected by urinary iodine measurements.
Keywords: Euthyroid goiter, Iodine deficiency
Turkiye Klinikleri J Med Sci 1996, 16:364-369
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