ISSN: 1300-0292 İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED CINAHL, Index Copernicus, Chemical Abstracts (CA), Excerpta Medica / EMBASE Dil: Türkçe, İngilizce İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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The Ultrastructure Of Kidneys On Experimental Diabetes Mellitus And The Improving Effects Of Selenium
Dr.Birkan YAKAN*, Dr.Mukaddes EŞREFOĞLU*
*Atatürk Üniversitesi Tıp Fakültesi Histoloji Embriyoloji AD, ERZURUM
In this study we aimed to investigate the renal ultrastructural pathological alterations in streptozotocin-included diabetic rats. THe major findings resulting from diabetes mellitus were the thickening of glomerular and tubular basement membranes and the proliferation of the mesengial cells. The other findings we observed were glycogen accumulation and increased vacuoles and lysosomes in the cytoplasms of the tubular cells. We observed the positive improving effects of selenium on these findings except the thickening of basement membranes.
Keywords: Streptozotocin diabetes, Kidney, Selenium
Turkiye Klinikleri J Med Sci 1995, 15:255-259
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