ISSN: 1300-0292 İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED CINAHL, Index Copernicus, Chemical Abstracts (CA), Excerpta Medica / EMBASE Dil: Türkçe, İngilizce İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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Moraxella (branhamella) Catarrhalis: The Role On Upper Respiratory Tract Infections, A Randomized Trial With The Comparison Of Ampicillin And Ampicillin-sulbactam Combination In The Ampirical Treatmen
Yrd.Doç.Dr.Dilara İÇAĞASIOĞLU*, Yrd.Doç.Dr.Esra BASKIN*, Yrd.Doç.Dr.Gülden KAFALI*, Dr.Funda KOÇOĞLU**, Yrd.Doç.Dr.Hayri B. TOKSOY*, Prof.Dr.Fatoş TANZER*
*Cumhuriyet Üniversitesi Tıp Fakültesi Çocuk Sağlığı ve Hastalıkları AD
**Cumhuriyet Üniversitesi Tıp Fakültesi Mikrobiyoloji Klinik Mikrobiyoloji AD, SİVAS
This study wan performed to find out the incidence of moraxella (Branhamella) catarrhalis in upper respiratory tract infections in childhood and to evaluate periodicity of dissemination. We also aimed to investigate the efficacy of Ampicillin and Ampicillin-Sulbactam combination on the treatment of its infections.
Nasopharingeal cultures were taken from 686 children aging between 3-16 years in the policlinics. Ampicillin was given to 346 patients (200 mg/kg/day 4xpo) and ampicillin-sulbactam was given to 340 patients (100 mg/kg/day 2xpo) during 5 days. Of 137 patients were excluded from this study because of not coming to control on the fifth day. M. Catarrhalis was found on the nasopharinks cultures with 16.2% incidances on 39 patients from ampicillin group and 50 patients from ampicillin-sulbactam group. The response of the treatment was superior in ampicillin-sulbactam group than Ampicillin group (p<0.0001).
Keywords: Moraxella catarrhalis, INfections, Ampicillin, Ampicillin-Sulbactam
Turkiye Klinikleri J Med Sci 1995, 15:244-247
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