ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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Vitamin E For Better Myocardial Protection In Coronary Artery Bypass Surgery
Yrd.Doç.Dr.M. Halit ANDAÇ*, Yrd.Doç.Dr.Naci EMİROĞULLARI*, Dr.Ramazan AŞIK*, Dr.Hakan CEYRAN*, Dr.Hasan YILMAZTÜRK, Dr.Metin AYIK*
*Erciyes Üniversitesi Tıp Fakültesi Göğüs ve Kalp-Damar Cerrahisi AD, KAYSERİ
The mechanism by which reperfusion may exacerbate myocardial ischemic injury has been extensively investigated in recent years. Oxygen-derived free radicals play a significant role in the pathogenesis of reperfusion injury, particularly by oxidiaing sarcolemmal phospholipids and thus distrupting membran integrity. Vitamin E or alpha-tocopherol is the major lipid-soluble antioxidant in the myocardial cell membranes.
In this study, we examined that reducing lipid peroxidation by means of exogenous antioxidants (vitamin E) might improve intraoperative myocardial protection.
Keywords: Vitamin E, Myocardial protection, Reperfusion injury
Turkiye Klinikleri J Med Sci 1995, 15:340-342
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