ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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Endothelin
Dr.Yavuz BAYKAL*, Dr.Salih PAY*, Dr.Gülsüm ÖZET**, Dr.Tahir ÜNAL*, Dr.Çağlayan ÖZDEMİR*, Dr.Ahmet ÖZET***, Dr.Fikri KOCABALKAN*
*GATA İç Hastalıkları Kliniği**Ankara Numune Hastanesi Hematoloji Kliniği***GATA Tıbbi Onkoloji BD, ANKARA
Endotelin (ET) is a potent vasoconstructive which has 21 amino acid peptide. Supsequent analysis of ET genes revealed the existence of three similar but distinct ET genes encoding different mature ET sequences that have been designated as ET-1, ET-2 and ET-3. These three isoforms are distributed widely in many tissues in different proportions. ET not only has a vasoconstructive action but also other functions, including vasodilative action, cell proliferating action, and diuretic action, among others. THe diversity of the pharmacological actions of ET has also been ascribed to a wide distribution of ET receptors in different cells.
Keywords: Endothelin
Turkiye Klinikleri J Med Sci 1996, 16:8-12
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