ISSN: 1300-0292 İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED CINAHL, Index Copernicus, Chemical Abstracts (CA), Excerpta Medica / EMBASE Dil: Türkçe, İngilizce İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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Superantigens
Doç.Dr.A. Eftal YÜCEL*, Dr.Ayşegül YÜCEL**
*İnönü Üniversitesi Tıp Fakültesi Romatoloji BD, MALATYA
**Gazi Üniversitesi Tıp Fakültesi İmmünoloji Doktora Öğrencisi, ANKARA
Superantigens are important structures that have been studied intensively in recent years. Superantigens are bacterial, mycoplasmal, viral and retroviral proteins which can activate more potently and a larger proportion of T cells than the normal antigens and probably play a role in the etiopathogenesis of autoimmune diseases. In this review, the different types of superantigens, how they activate T cells, immune response after activation and the role of the superantigens in the etiopathogenesis of some diseases, will be discussed.
Keywords: Superantigens, Otoimmunity, T cell activation
Turkiye Klinikleri J Med Sci 1996, 16:1-7
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