ISSN: 1300-0292 İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED CINAHL, Index Copernicus, Chemical Abstracts (CA), Excerpta Medica / EMBASE Dil: Türkçe, İngilizce İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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Normotensive Renal Failure Developed In Dermatomyositis Associated With Systemic Sclerosis
Dr.Sabahattin GÜL*, Dr.T. Rıfkı EVRENKAYA**, Dr.A. Kemal GÜRBÜZ*, Dr.Alp GÜNAY*, Dr.Mehmet DANACI*, Dr.M. Yaşar TÜLBEK*, Dr.Levent MERİÇ***
*GATA Haydarpaşa Eğitim Hastanesi İç Hastalıkları Kliniği
**GATA Haydarpaşa Eğitim Hastanesi Nefroloji Kliniği
***GATA Haydarpaşa Eğitim Hastanesi Anestezi Kliniği, İSTANBUL
Dermatomyositis (DM) is the nonsuppurative inflammation of the skeletal muscle with dermal rashes. One third of the cases have an overlapping connective tissue disease or malignancy may be seen alone or with overlap syndromes, characterized by systemic fibrosis. A serious and life-threatening complication of SCL is ?Scleroderma Renal Crisis? which is characterized by accelerated-malignant hypertension. Normotensive renal crisis may be seen in glucocorticoid-treated SCL patients. Normotensive SCL renal crisis is a syndrome characterized by microangiopathic hemolytic anemia, thrombocytopenia, pulmonary hemorrhage, recent prior corticosteroid use and poor outcome. Here we report a case of 22-year old scleroderma-overlapped dermatomyositis whose diagnosis established on Bohan-Peter criteria and treated with corticosteroids. She developed acute renal failure (ARF) in the fifth week of the treatment. She was given high dose captopril after the diagnosis of SCL kidney established by renal biopsy. Although she was maintained on haemodialysis five times, she had a fatal outcome on the fourteenth day of normotensive ARF.
Keywords: Scleroderma, Dermatomyositis, Acute renal failure
Turkiye Klinikleri J Med Sci 1996, 16:241-244
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