07-07-2008

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ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri

 
The Diagnostic Value Of Myocardial Perfusion Imaging Method With Stress Thallium-201 Spect In The Coronary Heart Disease

Uz.Dr.Sevgi YALIN*, Uz.Dr.Nermin AYDIN*, Uz.Dr.Cahit KOCAKAVAK*

*Ankara Eğitim Hastanesi 1. Dahiliye Kliniği, ANKARA



The aim of this study is to investigate the diagnostic value of myocardial perfusion imaging with stres, Thallium-201 SPECT in the diagnosis of coronary heart disease, accepting coronary angiography as the gold Standard. 176 patients were studied, including 119 (66%) men and 57 (32%) women with a mean age of 46±8 years. Exercise Tl-201 SPECT with stres-rest protocol and following within 20 day coronary angiography and left ventriculography were performed in all cases. Accepting coronary angiography as the Standard, the sensitivity, specificity and accuracy of the method of Stres Tl-201 SPECT in predicting coronary artery disease has been calculated in ventricul segments bases. The sensitivity, specificity and accuracy in predicting ventricular ischemia were found as 91%, 53% and 63% for anterior segment; 87%, 56% and 64% for septal segment; 72%, 87% and 83% for apical segment; 83%, 81% and 81% for lateral segment; 100%, 45% and 56% for inferior segment.
False positive results were due to mitral valve prolapse, left bundle branch block, right bundle branch block, muscular bridge, hypertension, diabetes mellitus cardiomyopathy and congenital fistulae of the coronary arteries (LAD) communicating with left ventricul.
In conclusion, it was accepted that the method of myocardial perfusion imaging with stress thallium-201 SPECT has been a valuable diagnostic method in the diagnosis of coronary artery disease and its sensitivity and specificity is higher as compared with exercise electrocardiography. However, particularly in the inferior segment, it was recorded a low specificity caused by false positive results.


Keywords: Stres Thallium-201 SPECT, MYocardial perfusion imaging, Coronary artery disease

Turkiye Klinikleri J Med Sci 1996, 16:272-276

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