ISSN: 1300-0292 İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED CINAHL, Index Copernicus, Chemical Abstracts (CA), Excerpta Medica / EMBASE Dil: Türkçe, İngilizce İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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Salivary Duct Carcinoma Ex Pleomorphic Adenoma Of The Parotid Gland: A Case Report
Nurper ONUK FİLİZ, MD, a R. Doğan KÖSEOĞLU, MD, a Ahmet EYİBİLEN, MD, b İbrahim ALADAĞ, MD, b Mehmet GÜVEN, MD, sup>b
Departments of a Pathology, b Ear Nose Throat and Head and Neck Surgery, Gaziosmanpaşa University School of Medicine, TOKAT Salivary duct carcinoma is a highly malignant salivary gland tumor with aggressive clinical behavior that has similar histological features with invasive ductal carcinoma of the breast. Malignant salivary gland tumors are rarely derived from preexisting pleomorphic adenoma (PA). Carcinoma ex PA is defined as a malignant epithelial neoplasm arising in association with a primary or recurrent PA and it accounts for approximately 2-5% of all PAs. Most of these tumors are located in the major salivary glands, particularly in the parotid gland. Fine-needle aspiration (FNA) biopsy is widely used as a diagnostic tool for the initial evaluation of parotid gland masses. The cytologic appearance of most PAs are characteristic. Although it is not difficult to recognize a PA, malignant tumors originating from PA may present a diagnostic problem. We report here a case of salivary ductal carcinoma ex PA of the parotid gland diagnosed by FNA biopsy and discuss the possible problems in diagnosis.Keywords: Adenoma, pleomorphic; salivary gland neoplasms; biopsy, fine-needleTurkiye Klinikleri J Med Sci 2008, 28:95-99
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