ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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Splenic Infarction In Wegener’s Granulomatosis: Case Report
Dr. Dilek SOYSAL,a Dr. Özlem YERSAL,a Dr. Volkan KARAKUŞ,a Dr. Ayşin HARMANDA,a Dr. Zeynep BAŞER,b Dr. Serpil YILMAZa
a1. Dahiliye Kliniği, Atatürk Eğitim ve Araştırma Hastanesi, bİzmir Suat Seren Göğüs Hastalıkları Hastanesi, İZMİR
Wegener’s granülomatosis is a systemic illness characterized by granülomatous vasculitis, which mainly affects the upper and lower respiratory tract and kidney. Although spleen involvement was reported histologically in a high proportion of patients in postmortem studies, clinical manifestation in living patients are rare. We report a 32 year-old woman with Wegener’s disease who was anticoagulated for deep venous thrombosis. In the clinical course, splenic infarction was demonstrated. She died following a hypotensive period, which was associated with splenic hemorrhage, but autopsy was not possible. This report highlights that although clinical manifestation of splenic infarction is a rare finding, anticoagulation may trigger splenic rupture or hemorrhage. Patients with Wegener’s granülomatosis must be evaluated with abdominal computed tomography before anticoagulation is started.Keywords: Wegener’s granülomatosis; vasculitis; splenic infarctionTurkiye Klinikleri J Med Sci 2007, 27:783-787
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