ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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Adult Langerhans Cell Histiocytosis: Differential Diagnosis
Dr. Timuçin ÇİL,a Dr. Deniz GÖKALP,b Dr. Alparslan TUZCU,b Dr. Abdurrahman IŞIKDOĞAN,a Dr. Mithat BAHÇECİb
aMedikal Onkoloji BD,b Endokrinoloji BD, Dicle Üniversitesi Tıp Fakültesi, DİYARBAKIR
Langerhans cell histiocytosis is a group of idiopathic disorders characterized by the abnormal proliferation of specialized bone mar-row-derived Langerhans cells. There are one to two cases per million population. Most reports are based only on anecdotal experience in adult patients. Surgical excision, radiotherapy and chemotherapy, either alone or in combination are the main treatment options. In this report, we present a rare case of Langerhans cell histiocytosis in a 32 years-old-woman who developed symptomatic diabetes insipidus and multiple bone and cranial metastases during the disease course. This paper discusses controversial treatment modalities.Keywords: Bone and bones; diabetes insipidusTurkiye Klinikleri J Med Sci 2007, 27:633-635
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