ISSN: 1300-0292 İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED CINAHL, Index Copernicus, Chemical Abstracts (CA), Excerpta Medica / EMBASE Dil: Türkçe, İngilizce İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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Prognoztic Factors In Non-small Cell Lung Cancer: Review
Dr. Arzu YAREN,a Dr. İlhan ÖZTOPb
aİç Hastalıkları AD, Tıbbi Onkoloji BD, Pamukkale Üniversitesi Tıp Fakültesi, DENİZLİbDokuz Eylül Üniversitesi Onkoloji Enstitüsü, İZMİR Lung cancer is the leading cause of cancer-related mortality in both genders worldwide. Non-small cell lung cancer (NSCLC) represents about 80% of all lung cancers. Less than one-third of these patients present at an early stage, and substantial relapses are observed despite curative surgical treatment. For the most part, recurrences occur at extrathoracic sites as distant metastases. The remaining patients have advanced disease and treatment is only marginally effective in such patients. Thus, prognoztic factors continue to play a critical role in the prediction of outcome in such patients. Early investigations that mostly focused on clinical characteristics of the tumor and the patient were followed by a number of clinical laboratory tests. Recently, studies that investigate the prognoztic significance of novel factors related to cellular and molecular biology of lung cancer have increased. The aim of this study was to review the literature with regard to prognoztic factors in patients with NSCLC.Keywords: Carcinoma; non-small-cell lung; prognozisTurkiye Klinikleri J Med Sci 2007, 27:72-78
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