ISSN: 1300-0292 İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED CINAHL, Index Copernicus, Chemical Abstracts (CA), Excerpta Medica / EMBASE Dil: Türkçe, İngilizce İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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Adjuvant Chemotherapy For Early-stage Non-small Cell Lung Cancer: Review
Dr. Arzu YAREN,aDr. İlhan ÖZTOPb
aİç Hastalıkları AD, Tıbbi Onkoloji BD, Pamukkale Üniversitesi Tıp Fakültesi, DENİZLİ
bDokuz Eylül Üniversitesi Onkoloji Enstitüsü, İZMİR Lung cancer is the leading cause of death in the world. Non-small cell lung cancer (NSCLC) represents about 80% of the all lung cancers. Less than one-third of these patients present with early stage cancer and substantial relapses are observed despite curative surgical treatment. Recurrences are usually in the form of extrathoracic and distant metastases. Until recently, in the vast majority of studies involving postoperative treatments including chemotherapy and/or radiotherapy, no substantial survival advantage was demonstrated. Recent reports within the last 2 years with results favoring adjuvant chemotherapy, led to the consideration of adjuvant chemotherapy again. This review aims to summarize the role of adjuvant chemotherapy by evaluating novel adjuvant chemotherapy studies and meta-analyses for the use of this treatment modality in resected NSCLC.Keywords: Carcinoma, non-small-cell lung, chemotherapy, adjuvantTurkiye Klinikleri J Med Sci 2006, 26:649-654
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