ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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ORIGINAL RESEARCH ARTICLES |
Detection Of Apoptosis Feature In Ultraviolet Light-exposed Trichophyton Rubrum
Payam BEHZADI,a Elham BEHZADIb
Departments of aMicrobiology, bBiology, Azad University, IRAN
Objective: The aim of this study was to detect the apoptosis feature following the ultraviolet (UV)-light irradiation in Trichophyton rubrum and analyze the results in molecular aspect.
Material and Methods: The colonies of T. rubrum were irradiated by UV light at a wavelength of 302 nm. For observing the possible apoptosis feature, the high-molecular-weight DNA was isolated from non-irradiated and irradiated colonies of T. rubrum respectively and then were run through 1% agarose gel.
Results: In the investigation of isolated DNA molecules, no differences between DNA banding patterns were observed.
Conclusion: By the performed protocol in this project, no phenomenon of apoptosis was detected in the dermatophyte fungus of T. rubrum. The negative tropism of T. rubrum towards UVB may be the cause of no-apoptosis feature.Keywords: Hücre ölümü, TrichophytonTurkiye Klinikleri J Med Sci 2006, 26:607-610
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