ISSN: 1300-0292 İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED CINAHL, Index Copernicus, Chemical Abstracts (CA), Excerpta Medica / EMBASE Dil: Türkçe, İngilizce İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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Acute Respiratory Failure Due To Pulmonary Tuberculosis And Its Successful Treatment With Medical Therapy: A Case Report
Deniz KÖKSAL, MD,a Ayşenaz ÖZCAN, MD,a Şeref ÖZKARA, MDa
aClinics of Thorax Surgery, Atatürk Thorax Diseases and Thorax Surgery Training and Research Hospital, ANKARA A 64-year-old male patient who had been hospitalized in an otolaryngology clinic for the evaluation of hoarseness for 20 days was referred to our clinic due to sudden onset of respiratory distress. Indirect laryngoscopy revealed a mass lesion on epiglottis. The patient was severely hypoxemic. Chest radiography revealed bilateral reticulo-nodular infiltrates predominately on the middle zones, a fibrocavitary image and volume loss on right upper zone, blunting of right costophrenic angle and left pleural effusion. High flow oxygen therapy via nasal canule, an empirical regimen of antibiotics, corticosteroid, and diuretic was instituted. On the forth day of hospitalization sputum smear was positive for acid-fast bacilli and antituberculous therapy was immediately administered despite a mild elevation of liver function tests. After 10 days, due to the further elevation of liver function tests, antituberculous therapy was switched to a non-hepatotoxic regimen. The therapy was continued for 9 months. The mass lesion on the epiglottis disappeared after 2 months of therapy. In conclusion, it is essential to consider tuberculosis (TB) in the differential diagnosis of acute respiratory failure. Rapid diagnosis, immediate and continuous antituberculosis therapy is critical for a successful outcome and good prognosis.Keywords: Tuberculosis, respiratory insufficiency, therapyTurkiye Klinikleri J Med Sci 2006, 26:449-452
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