ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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Fibroblast And Fibroblast Like Cells: Medical Education
Dr. E. Elif GÜZEL,a Dr. Pergin ATİLLA,a Dr. Attila DAĞDEVİRENa
aHistoloji ve Embriyoloji AD, Hacettepe Üniversitesi Tıp Fakültesi, ANKARA
It is very difficult to distinguish genuine fibroblasts from a large population of fibroblast-like cells, which carry out different functions at different locations sharing certain characteristic features of fibroblasts. Fibroblast-like cells exhibit structural features and antigenic profiles related to their specific locations and functions. Examples of fibroblast-like cells are myofibroblasts, perineural sheath cells, Ito cells, endocrine fibroblast-like cells, pericryptal and villous fibroblasts in the intestine, fibroblast-like cells in the myenteric plexus, lymphoid organ dendritic cells and fibroblasts at different sites including tendon, dermis and cornea. Grouping of such a wide variety of cells in a fibroblast (-like) family arises both from structural findings and experimental studies demonstrating the fibroblastic origin of most of the members. This review summarizes the classical and current data about fibroblasts and a group of cells which possess common features with fibroblasts. Discrimination of a certain cell type or a cell group using clear-cut set of criteria will be possible if lineage specific markers are broadly accepted.Keywords: Fibroblasts, dendritic cellsTurkiye Klinikleri J Med Sci 2006, 26:421-429
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