ISSN: 1300-0292 İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED CINAHL, Index Copernicus, Chemical Abstracts (CA), Excerpta Medica / EMBASE Dil: Türkçe, İngilizce İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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ORIGINAL RESEARCH ARTICLES |
Effect Of Treatment On Echocardiographic Variables In The Follow-up Of Dilated Cardiomyopathy
Hakan ÖZHAN, MD,a Mustafa ZUNGUR, MD,b Ramazan AKDEMİR, MD,a Mehmet YAZICI, MD,a Sinan ALBAYRAK, MD,a Enver ERBİLEN, MDa
aDepartment of Cardiology, Düzce Medical Faculty of Abant İzzet Baysal University, DÜZCE
bClinic of Cardiology, Çağ Hospital, ANKARA Objective: Dilated cardiomyopathy (DCM) is a myocardial disease characterized by impaired systolic function and dilation of the left or both ventricles. Despite advances in the medical management of patients with DCM, the mortality rate for this condition remains high. The purpose of the present study was to assess the echocardiographic predictors of improvement in the follow-up of dilated cardiomyopathy.
Material and Methods: Sixty-six consecutive patients with DCM (left ventricular ejection fraction [LVEF] <40% at the initial assessment and left ventricular end diastolic diameter [LVEDD] >55 mm) diagnosed for the first time were included in the study. Demographic, clinical and echocardiographic variables were recorded. ACE inhibitor, diuretic and whenever possible digitalis, spiranolactone and beta-blocker therapy were administered to all of the patients. After 12 months of follow-up, echocardiographic analyses of the patients were reviewed and compared with the initial data.
Results: Four patients died during the follow-up period. The comparison of the final and initial data revealed a significant difference in LV mass (LVM), ejection fraction (EF), deceleration time (DT), ejection time (ET) and myocardial performance index (MPI).
Conclusion: LVM, EF, DT, ET and MPI changes significantly after medical treatment of DCM patients and can predict improvement in these patients.Keywords: Echocardiography, cardiomyopathy, dilatedTurkiye Klinikleri J Med Sci 2005, 25:776-780
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