ISSN: 1300-0292 İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED CINAHL, Index Copernicus, Chemical Abstracts (CA), Excerpta Medica / EMBASE Dil: Türkçe, İngilizce İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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ORIGINAL RESEARCH ARTICLES |
Erythroderma: A Retrospective Clinicopathological Evaluation Of 59 Cases
Dr. İlkin ZİNDANCI,a Dr. Mukaddes KAVALA,a Dr. Ebru ZEMHERİ,b
Dr. Burçe CAN,aDr. Emek KOCATÜRKa
aDermatoloji Kliniği, bPatoloji Kliniği, SB Göztepe Eğitim ve Araştırma Hastanesi, İSTANBUL Objective: Erythroderma is a condition with multiple etiologies characterized by erythema and desquamation involving the whole body or a significant portion of the body surface. In the present study, we examined the etiologic, clinical and laboratory features of patients with erythroderma and sought correlations.
Material and Methods: We reviewed the clinical and laboratory data contained in the inpatient records of 59 patients hospitalized in our clinic between 1994 and 2004. Patients were classified according to etiology into 4 groups: existing dermatoses, drug reactions, malignancies and idiopathic manifestation. Skin and/or lymph node specimens of 24 patients were then evaluated
Results: The mean age and male/female ratio was 45.5 and 2.1/1, respectively. The most common cause of erythroderma was dermatosis (59.3%), followed by drug reactions (27.1%). The correlation between clinic and histopathologic diagnoses was 83.3%. The diagnoses of fungoid mycoses could only be made on the basis of multiple skin biopsies. No specific laboratory findings were associated with erythroderma.
Conclusion: We conclude that erythroderma is more prevalent in older men and occurs mostly due to flare-ups of an existing dermatosis. An exact diagnosis can only be established on the basis of multiple biopsies.Keywords: Dermatitis,etiology,pathology,retrospective studiesTurkiye Klinikleri J Med Sci 2005, 25:525-529
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