ISSN: 1300-0292 İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED CINAHL, Index Copernicus, Chemical Abstracts (CA), Excerpta Medica / EMBASE Dil: Türkçe, İngilizce İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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Melanonychia And Xerosis Induced By Hydroxyurea Therapy: A Case Report
Dr. Ayça CORDAN YAZICI,a Dr. Kıymet BAZ,a Dr. Aynur KOCA,a
Dr. Ayşin KÖKTÜRK,a Dr. Güliz İKİZOĞLUa
aDermatoloji AD, Mersin Üniversitesi Tıp Fakültesi, MERSİN Hydroxyurea is a cytostatic agent that has been widely used for the treatment of myeloproliferative disorders and sickle cell anaemia. The side-effects of hydroxyurea therapy on skin, nail, bone marrow and gastrointestinal system have been reported. Nail hyperpigmentation and skin dryness developed in a 51-year-old male patient with polycytemia rubra vera following 2 months of hydroxyurea therapy. We present this case to stress the potential cutaneous side-effects of hydroxyurea therapy and to increase clinical awareness of the physicians.Keywords: Hydroxyurea, xerodermaTurkiye Klinikleri J Med Sci 2005, 25:452-454
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