ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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ORIGINAL RESEARCH ARTICLES |
Skin Findings In Patients With Type Ii Diabetes Mellitus
Dr. Yasemin SARAY,a Dr. Deren ÖZCAN,a Dr. Deniz SEÇKİNa
aDermatoloji AD, Başkent Üniversitesi Tıp Fakültesi, ANKARA
Objective: The aim of this study was to determine the clinical spectrum and incidence of skin lesions in patients with type II diabetes mellitus, and to investigate the relationship between these findings and age, sex, duration of diabetes, vascular complications, HbA1c levels and ongoing treatment.
Material and Methods: Eighty patients with type II diabetes mellitus who were followed at the Department of Endocrinology in the Bilkent University Faculty of Medicine underwent dermatological examination. Duration of disease, presence of vascular complications and type of treatment administered were recorded. HbA1c levels were determined.
Results: Of the 80 patients, 32 were male and 48 female, mean age was 58.7 and the mean duration of diabetes mellitus was 124.3 months. Vasculopathy [retinopathy (21.3%), neuropathy (17.5%), peripheral vascular disease (16.3%) and nephropathy (10%)] was present in 38.8% of the patients. The mean HbA1c level was 6.2%. Skin lesions (most frequently, xerosis (42.5%), plantar hyperkeratosis (36.3%), dermatophytic infections (27.5%), papilloma (25%), and pruritus (16.3%)) were observed in 76.3% of the patients. There was a statistically significant relationship between the frequency of dermatophytic infections and age, duration of diabetes mellitus and peripheral vascular disease (p= 0.04, p= 0.014 and p= 0.006, respectively). There was also a statistically significant relationship between the frequencies of xerosis and papilloma and the presence of nephropathy, as well as between the frequencies of thickened skin and candidiasis and the presence of neuropathy (p= 0.048, p= 0.004, p= 0.045 and p= 0.01, respectively).
Conclusion: Varying types of skin findings can be noted in patients with type II diabetes mellitus. Elderly patients with long-lasting diabetes mellitus and patients with peripheral vascular disease should be evaluated for dermatophytic infections. Moreover, patients with xerosis and papilloma, as well as those with thickened skin and candidiasis should be followed up for the presence of neuropathy.Keywords: Diabetes mellitus, type II, skin, complications, infectionTurkiye Klinikleri J Med Sci 2005, 25:377-382
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