ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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The Development Of Pigmented Purpuric Dermatosisin Two Cases With Hcv Infection
Zülal ERBAĞCI, A. Almıla TUNCEL
* Doç.Dr., Gaziantep Üniversitesi Tıp Fakültesi Dermatoloji AD,
**Dr., Gaziantep Üniversitesi Tıp Fakültesi Dermatoloji AD, GAZİANTEP
Background and Objective: The pigmented purpuric dermatoses are a group of disorders characterized clinically by usually asymptomatic pinpoint petechiae and nonpalpable purpura on a hyperpigmented base, and histologically by lymphocytic capillaritis. They include following clinical entities: progressive pigmentary purpuric dermatosis (Schamberg's disease), purpura annularis telangiectodes (Majocchi’s disease), pigmented purpuric lichenoid dermatosis (Gougerot and Blum's disease), itching purpura (Doucas and Kapetanakis’ eczematoid purpura) and lichen aureus. Although the etiopathogenesis is unknown, aberrant cell-mediated immunity has been proposed. Case Report: We describe herein two cases of pigmented purpuric dermatosis in association with HCV infection. While the first case seemed to be directly related to HCV infection, the eruption developed after initiation of high-dose interferon-alpha (IFN-α) therapy for chronic C hepatitis in the second case.Conclusion: As our cases indicate possible etiopathogenetic relationships between pigmented purpuric dermatoses and HCV infection as well as its management with IFN-α, it would be appropriate to search these conditions, which are well known for their immune modulating capacity in patients presenting with these dermatoses.Keywords: Skin Diseases, Hepatitis C, Interferon-alphaTurkiye Klinikleri J Med Sci 2003, 23:238-241
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