ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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Anesthetic Management In Myasthenic Patients Without Myorelaxant(three Cases Report)
Ahmet MAHLİ*, Özgür ALDEMİR**, Demet COŞKUN***
Mehmet AKÇABAY****, Şahin YARDIM*****
* Yrd.Doç.Dr., Gazi Üniversitesi Tıp Fakültesi Anesteziyoloji ve Reanimasyon AD,
** Uz,Dr., Fatih Üniversitesi Tıp Fakültesi Anesteziyoloji ve Reanimasyon AD
*** Uz.Dr., Gazi Üniversitesi Tıp Fakültesi Anesteziyoloji ve Reanimasyon AD,
**** Doç.Dr., Gazi Üniversitesi Tıp Fakültesi Anesteziyoloji ve Reanimasyon AD,
***** Prof.Dr., Gazi Üniversitesi Tıp Fakültesi Anesteziyoloji ve Reanimasyon AD, ANKARA
Anaesthesia has been planned without myorelaxant in anaesthesia induction and maintenance for thymectomy and neurectomy operations in three patients diagnosed as myasthenia gravis. As an anaesthetic induction each patient received 7 mg kg-1 thiopenthal-Na intravenously and ventilation was assisted by O2/N2O (2/4 L/min) and 1.5-2 Vol % end-tidal enflurane via mask for two minutes. When the depth of anaesthesia was adequate, the patient was intubated without any problem and anaesthesia was maintained with 1-1.25 Vol. % end-tidal enflurane until the end of the operation. Muscle activities were recorded by relaxograph. A patient at approximately the same age and with no systemic disease was selected to understand the degree of depressing effect of enflurane on muscle activity. This trace of a nonmyasthenic patient was helpful in understanding the traces of myasthenic patients. Muscle activities of this nonmyasthenic patient were recorded under enflurane anesthesia without administrating any muscle relaxant. Decreases in T1 % and train of four (TOF) % were recorded maximally up to 26% and 15% respectively in our clinically most serious myasthenic patient (Type III). The depression of muscular activity in our myasthenic patients was found nearly the same with nonmyasthenic patient.Keywords: Enflurane, Myasthenia gravis, Neuromuscular blockingTurkiye Klinikleri J Med Sci 2002, 22:308-312
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