ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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Carcinosarcoma (true Malignant Mixed Tumor) Of The Submandibular Salivary Gland
Kısmet BİLDİRİCİ*, Özlem EREN*
* MD., Department of Pathology, Osmangazi University School of Medicine, Eskişehir, TURKEY
Introduction: Carcinosarcoma (true malignant mixed tumor) of salivary gland origin are a very rare and extremely aggressive neoplasm. By definition, it is composed of both malignant epithelial and malignant mesenchymal elements. Case Report: We report a rare case of submandibular salivary gland carcinosarcoma (true malignant mixed tumor) which occured in a 72-year-old women. At histologic examination, the tumor showed biphasic differentiation with an epithelial component made up of well-differentiated squamous carcinoma, and a mesenchymal component, revealing fibrosarcoma. Immunohistochemical studies confirmed two separete populations of tumor cells, corresponding to the histologic growth pattern. Conclusion: Carcinosarcomas are aggressive neoplasms which in general rapidly develop metastasis or recur after resection and have a poor prognosis despite therapyKeywords: Carcinosarcoma, Mixed Tumor, Malignant, Submandibular Gland NeoplasmsTurkiye Klinikleri J Med Sci 2003, 23:146-149
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