ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
|
|
|
|
ORIGINAL RESEARCH ARTICLES |
Effects Of Short-period Pharmacotherapy On Heart Rate Reserve And Exercise Performance In Obese Patients
Oğuz ÖZÇELİK*, Ramis ÇOLAK**
* Yrd.Doç.Dr., Fırat Üniversitesi Tıp Fakültesi Fizyoloji AD,
** Yrd.Doç.Dr., Fırat Üniversitesi Tıp Fakültesi Endokrinoloji ve Metabolizma Hastalıkları BD, ELAZIĞ
Purpose: To examine the effects of weight loss induced by pharmacotherapy on heart rate reserve and exercise performance in obese patients.
Materials and Methods: Twelve obese female (Body Mass Index, 35.7±3 kg/m2) were received a hypocaloric diet and 3x120 mg/day orlistat therapy for a period of 4 weeks. Body composition was determined using leg-to-leg bioelectrical impedance analysis method. Each patient performed two incremental (15 W/min) exercise tests (at onset and at 4 week) using elektomagnetically-braked cycle ergometer to determine work rate production capacity. Anaerobic threshold (aerobic-anaerobic metabolic transition) was estimated non-invasively using ventilation-metabolic relationship. Heart rate was monitored using polar heart watch.
Results: During therapy, total body weight (89.8±11 kg–86.5±11 kg) and fat mass (37.7±7.0 kg–36.3±7.8 kg) reduced significantly. Heart rate reserve did not change significantly: 80.8±19 beat (basal) and 76.4±15 beat (4-wk). Maximal work rate (Wmax) was not different between basal (90±18 W) and after treatment (92±17 W). Heart rate at rest was 86.6±14 beat/min (basal) and 86.5±14 beat/min (4-wk). During warm-up period it increased to 135.1±13 beat/min (basal) and 128.8±21 beat/min (4-wk), i.e. 60% and 55% of heart rate reserve. At the anaerobic threshold, heart rate was 151.8±15 beat/min (basal) and 142.2±19 beat/min (4-wk), i.e. 81% and 79% of heart rate reserve. Heart rate at Wmax was 167.5±15 beat/min (basal) and 162.9±16 beat/min (4-wk), i.e. 92% and 90% of predicted heart rate.
Conclusion: Ineffective utilisation of heart rate reserve reduced work production capacity and weight loss induced by drug and diet did not effect positively on heart rate reserve and work rate production capacity. Thus, it should be considered an proper programme in obesity treatment which provides an effective utilisation of heart rate reserve.Keywords: Exercise Test, Obesity, Heart RateTurkiye Klinikleri J Med Sci 2003, 23:115-119
|
|
|
|
|
