ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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The Pathogenesis And Treatment Ofseborrhoeic Dermatitis
H. Serhat İNALÖZ*, Necmettin KIRTAK**
* Assist.Prof., Department of Dermatology University of Wales College of Medicine, Cardiff, UK &
Department of Dermatology University of Gaziantep Faculty of Medicine, Gaziantep, TURKEY
** Assist.Prof., Department of Dermatology University of Gaziantep Faculty of Medicine, Gaziantep, TURKEY
The importance of seborrhoeic dermatitis has increased again among dermatologists after the AIDS epidemic. Infantile seborrhoeic dermatitis and adult seborrhoeic dermatitis are regarded as different entities. Pathogenesis of infantile and adult seborrhoeic dermatitis are multifactorial. Several mechanisms such as maternal hormones, nutritional factors, atopic diathesis, biotin deficiency, decreased D-6-desaturase activity and Pityrosporum ovale play roles in the pathogenesis of infantile seborrhoeic dermatitis. The amount and composition of skin lipids, different strains of Pityrosporum ovale, lipase activity, specific immune reactions against Pityrosporum ovale, heredity, the work environment and mental stress have an influence on the pathogenesis of adult seborrhoeic dermatitis. Topical imidazole derivatives and topical lithium ointment are more effective than the other topical remedies in treatment. Systemic treatment such as antihistamines, isotretinoin, ketoconazole, itraconazole, fluconazole or terbinafine can be administered in severe cases.Keywords: Seborrhoeic DermatitisTurkiye Klinikleri J Med Sci 2002, 22:239-244
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