ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
|
|
|
|
ORIGINAL RESEARCH ARTICLES |
Radiotherapy In Meningioma: Retrospective Analysis Of Recurrent Andmalignant Cases
H.Cüneyt ULUTİN*, Metin GÜDEN*, Yücel PAK**
* Yrd.Doç.Dr., GATA Radyasyon Onkolojisi AD,
** Prof.Dr., GATA Radyasyon Onkolojisi AD, Başk., ANKARA
Purpose: To evaluate the efficacy and morbidity of radiotherapy in malignant or recurrent meningiomaInstution: GATA Department of Radiation Oncology- Ankara Materials and Methods: This study was performed on 37 patients who had radiotherapy for meningioma between 1980 to 1999. Except one inoperable patient, all patients received postoperative cranial local field external radiotherapy with Co-60 device. Total of 48 to 66 Gy (median 56 Gy) radio-therapy doses were given with 2 Gy fraction dose. Early and late morbidities related to treatment were evaluated according to EORTC/RTOG morbidity scale.Results: Twenty-four male and thirteen female patients, total of 37 followed-up 7 years (ranged 3 to 18 years. Median age was 57 years (23 to 68 years). Recurrence was observed in one patient treated with only radiotherapy, in three patients reoperated for recurrence, and in three patients who had malign histopathologic features. Time to recurrence after treatment (radiotherapy) was 3.8 years. Total local control rate was 81%. 5- year and 10-year survival rates were 82% and 70%, respectively. Alopecia was observed in all patients. Although no cranial nerve pathology was observed, one patient who was reirradiated for recurrence had focal glial necrosis.Conclusion: As a result, conventional radiotherapy can be successfully and safely applied for meningioma postoperatively.Keywords: Meningioma, Malignant, Recurrence, RadiotherapyTurkiye Klinikleri J Med Sci 2002, 22:109-112
|
|
|
|
|
