ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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Effects Of Propofol Anaesthesia On Cerebral Blood Flowand Somatosensory Evoked Potentials In Dogs
Uğur EROL*, Ülkü AYPAR**, Kemal ERDEM**,Kadir TAHTA***,Tülin ARAS****, Meral TOPÇU*****
* Uz.Dr.,Hacettepe Üniversitesi Tıp Fakültesi, Anesteziyoloji ve Reanimasyon AD,** Prof.Dr.,Hacettepe Üniversitesi Tıp Fakültesi, Anesteziyoloji ve Reanimasyon AD,*** Doç.Dr.,Hacettepe Üniversitesi Tıp Fakültesi, Beyin Cerrahisi AD,**** Doç.Dr.,Hacettepe Üniversitesi Tıp Fakültesi, Nükleer Tıp AD,***** Doç.Dr.,Hacettepe Üniversitesi Tıp Fakültesi, Çocuk Hastalıkları AD, ANKARA
Effects of propofol anaesthesia on cerebral bloo flow and somatosensory evoked potentials in dogs were investigated. Seven mongreal dogs were included in the study. Cerebral blood flows were measured following the use of ketamine 10 mg/kg and xylazine 2 mg/kg im for immobilization and anaesthesia of the dogs and were considered as basal values. Anaesthesia was maintained with propofol infusion in a dose of 16 mg/kg/hr and the measurements were repeated after one hour.
Arterial blood pressure and blood gas values were monitorized via a femoral catheter. Xenon 133 was given to measure cerebral blood flow via a catheter introduced into internal carotid artery and somatosensory evoked potentials were noted simultaneously.
Cerebral blood flow was found to be in the normal range throughout the study. There was no significant change in the amplitude of the somatosensory evoked potentials and latency period was not prolonged (p>0.05).
In conclusion; cerebral blood flow was not adversely effected and maintained in the normal physiological range during propofol anesthesia.
Keywords: Propofol, Cerebral blood flow,
Somatosensory evoked potentials
Turkiye Klinikleri J Med Sci 1998, 18:44-49
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