ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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Plasma Lipid Peroxidation In Adult Smokers
Mehmet ÜNLÜ*, Veysel TAHAN**, Ahmet AKKAYA***, Mustafa DEMİRCİ****, Ünal ŞAHİN*****
* Arş.Gör.Dr.,Süleyman Demirel Üniversitesi Tıp Fakültesi Göğüs Hastalıkları AD,
** Arş. Gör.Dr.,Süleyman Demirel Üniversitesi Tıp Fakültesi Biyokimya AD,
*** Doç.Dr.,Süleyman Demirel Üniversitesi Tıp Fakültesi Göğüs Hastalıkları AD,
**** Arş.Gör.Dr.,Süleyman Demirel Üniversitesi Tıp Fakültesi Mikrobiyoloji AD,
Oxygen free radicals are known to make damage in many biological tissues. Cigarette smoking is a major risk factor for various diseases. It is possible that oxygen free radicals produced by the activity of polymorphonuclear leucoytes is increased by cigarette smoking. In this study markers of free radical activity (thiobarbituric acid reactivity - malondialdehyde, superoxide dismutase) were measured in adult smokers and nonsmoker volunteers. The plasma MDA levels in smoking groups (1.48±0.11 nmol/ml) were higher as compared to non smokers (0.99±0.15 nmol/ml, p<0.01) and erythrocyte SOD levels were not different statistically (p>0.05).
According to these results, the elevated MDA levels can indicate that smoking leads to oxidative changes in biologic molecules in adult smokers.
Keywords: Cigarette, Malondialdehyde,
Superoxide dismutase
Turkiye Klinikleri J Med Sci 1998, 18:105-108
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