ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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Heparin Induced Thrombocytopenia (hit)
Serap ERDOĞDU ESİN*, Géza LUPKOVICS*, Bahriye PAYZİN**, Rainer ARENDT*
* Dr.Ludwig Maximilian Üniversitesi Grosshadern Hastanesi I. Dahiliye Servisi Münih, ALMANYA** Dr.Atatürk Devlet Hastanesi, İZMİR
Heparin induced thrombocytopenia (HIT) is divided into two types. Type I is the mild form of HIT, that occures about 10-30 per cent of patients. There is no complication and the mechanism is the inhibition of adenyl-cylase.
Type II occurs only 0.5-5 per cent, but produces severe morbidity and mortality. After starting heparin therapy, because of immune mechanism, severe thrombocytopenia appears in 6-14 days. The severe form of HIT may be associated with both arterial and venous thrombosis. These thrombotic complications frequently result in serious consequences, such as leg amputation, hemiplegia and can even cause death.
In this report we present a case of HIT type II.
Keywords: Heparin, Thrombocytopenia
Turkiye Klinikleri J Med Sci 1998, 18:127-131
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