ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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Sertraline In The Treatment Ofpremature Ejaculation:a Double-blind Placebo Controlled Study
Hasan Bİrİ*, Kenan İSEN**, Zafer SInIk***, Metin Onaran**,
Bora Küpelİ***, İbrahim BozkIrlI****
* Yrd.Doç.Dr.,Gazi Üniversitesi Tıp Fakültesi Üroloji AD,
** Araş.Gör.Dr.,Gazi Üniversitesi Tıp Fakültesi Üroloji AD,
*** Uz.Dr.,Gazi Üniversitesi Tıp Fakültesi Üroloji AD,
**** Prof.Dr.,Gazi Üniversitesi Tıp Fakültesi Üroloji AD, ANKARA
This study investigated the efficacy and the adverse effects of sertraline in the treatment of premature ejaculation (PE). Thirty-seven patients with PE were randomly assigned to receive either sertraline or a placebo. The study group excluded those with psychiatric and neurological disorders, urogenital infections and drug or alcohol abuse. In this double-blind study, twenty-two of them were given 50 mg of sertraline perday and the another 15 patients were given an identical placebo one perday. After 4 weeks, they were evaluated for latency to ejaculation and side effects of the drug. The latency to ejaculation in the sertraline group was found to be significantly longer than that of the placebo group (p<0.01). No patients discontinued therapyy due to adverse effects. Four weeks after the end of the therapy, PE recurred in 19 (86.36%) patients who received sertraline. These result indicate that sertraline is an effective therapy for PE.
Keywords: sertraline, premature ejaculation,
antidepressant drug
Turkiye Klinikleri J Med Sci 1998, 18:176-179
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