ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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Bacterial Translocation After Intraperitoneal Drain In The Splenectomized Rats
Mahmut BAŞOĞLU*, Mehmet İlhan YILDIRGAN*, Kamil Yalçın POLAT*,Cemal GÜNDOĞDU**, İbrahim KAVAK*, Selahattin ÇELEBİ***
* Dr.,Atatürk Üniversitesi Tıp Fakültesi Genel Cerrahi AD,** Dr.,Atatürk Üniversitesi Tıp Fakültesi Pataloji AD,
The aim of this study was to investigate the possible presence of bacterial translocation associated with the use of abdominal rubber drains and the effect of splenectomy to this event. For this purpose, healthy Wistar Albino rats were used. Animals were divided into 4 groups, each containing 10. In group I: sham-operation, in group II: intraperitoneal rubber drain, in group III: splenectomy plus intraperitoneal rubber drain and group IV splenectomy were peformed. Rubber drain was insided into peritoneum one week after laparotomy. Two days after rubber drain implantation, relaparotomy was done. Specimens from liver, lung, kidney, blood and MNL were obtained. Additionally, cecum was excised and luminal content was taken for culture. No grow was seen in blood cultures. Bacterial translocation was found significantly higher in group II than in other groups. It was seen that formation of bacterial colonisation was also considerably prominent in group II when compared to other groups. Histopathologic evalution showed that in splenectomy-applied groups, barrier of ileal mucosa was protected and inflammatory cell infiltration was lower.
As a conclusion, we observed that bacterial translocation occured with intraperitoneal biomaterials and splenectomy decreased the rate of bacterial translocation.
Keywords: Bacterial translocation, Splenectomy
Turkiye Klinikleri J Med Sci 1998, 18:190-195
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