ISSN: 1300-0292 İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED CINAHL, Index Copernicus, Chemical Abstracts (CA), Excerpta Medica / EMBASE Dil: Türkçe, İngilizce İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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Morphologic And Morphometric Differences Of Testis Tissue Onl-carnitine Treated Rats
Ömer Coşkun*, Recep Kutlubay**, Birkan Yakan***,
Oğuz Ekmekçİoğlu*, Ömer Öztürk*
* Dr.,Erciyes Üniversitesi Tıp Fakültesi Histoloji-Embriyoloji AD,
** Yrd.Doç.Dr.,Erciyes Üniversitesi Tıp Fakültesi Histoloji-Embriyoloji AD,
*** Doç.Dr.,Erciyes Üniversitesi Tıp Fakültesi Histoloji-Embriyoloji AD, KAYSERİ
Morphologic and morphometric effects of L-carnitine on testis tissue were studied using 20 adult male Wistar rats.
The rats were divided two groups, experimental and control, and each group was 10 male rats. While 300 mg/kg/day L-carnitine was given orally to experimental group, same amount 0,09% NaCl was given to control group during three days.
After three days, the testis tissues were taken from both groups and slides pepared for light microscopy. The morphologic and morphometric changes of the testis were assessed using light microscopy.
When experimental group was compared to control group; the number of spermatogonium which were mitosis phase increased. Also there were distinguishable increase in number of spermium tubul lumen and in ductus epididymidis. Furthermore, there were granuler increase in Leydig cell cytoplasm, and the cytoplasm were found more light and eosinophilic. However, there were decrease in epithelial length in ductus epididymidis of experimental group.
Keywords: L-carnitine, Testis, Rat
Turkiye Klinikleri J Med Sci 1998, 18:236-239
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