|
An Evaluation Of 50 Sarcoidosis Cases
Ayşegül KARALEZLİ*, Meftun ÜNSAL**, Cem GÜNDOĞDU***, Güngör DURSUN*, Yılmaz BAŞER*
* Dr.,Atatürk Göğüs Hastalıkları ve Cerrahisi Merkezi, ANKARA
** Dr.,Ondokuz Mayıs Üniversitesi Tıp Fakültesi Göğüs Hastalıkları AD, SAMSUN
*** Dr.,Bayındır Tıp Merkezi, ANKARA
In this research, 34 female and 16 male patients, diagnosed as sarcoidosis at Chest Disease and Thoracic Surgery Center, were studied. The mean age of female patients was 44(15-71) and of male patients was 36(19-66).
All of the cases were diagnosed histopathologically. While 38% of cases were diagnosed by transbronchial lung biopsy (TBAB), 32% were diagnosed by scalen lymph node biopsy, 16% by open lung biopsy and 12% by peripheric lymph node biopsy. The most frequent symptomps were nonproductive cough (48%) and dyspnea (48%). The mostly seen extrapulmonary involvement was peripheric lymph nodes (12%) and skin (10%) respectively. Radiologically, 54% of cases were defined as stage I, 40% as stage II and 6% as stage III.
PPD was negative in 82% of cases.
While in 23% of 26 cases serum angiotensin converting enzyme level was high, broncoalveolar lavage angiotensin converting enzyme level was found to be high in 60% of 10 cases.
Ga uptake was seen in 85% of 20 cases.
It’s observed that 87.5% of cases in stage I and 77% of cases in stage II have gone to complete remission with treatment.
Keywords: Sarcoidosis, clinical features, diagnosis,
serum angiotensin converting enzyme,
broncoalveolar lavage angiotensin
converting enzyme, Ga 67 scanning,
carbon monoxide diffusing capacity (DLCO),
pulmonary function testing, treatment
Turkiye Klinikleri J Med Sci 1998, 18:245-254
|
