ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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ORIGINAL RESEARCH ARTICLES |
Effects Of Urapidil On Haemodynamic Response To Endotrachealintubation And Sternotomy In Open Heart Surgery
Mehmet AKÇABAY*, Berrin GÜNAYDIN**, Yener KARADENİZLİ***
* Doç.Dr.,Gazi Üniversitesi Tıp Fakültesi Anesteziyoloji AD,
** Uz.Dr.Gazi Üniversitesi Tıp Fakültesi Anesteziyoloji AD,
*** Prof..Dr.Gazi Üniversitesi Tıp Fakültesi Anesteziyoloji AD, ANKARA
38, ASA II or III subjects (18 female and 20 male) undergoing coronary artey bypass surgery were administered i.v. urapidil before intubation and sternotomy to demonstrate the effects of cardiac and circulatory haemodynamic responses. Following i.v. 0.04 mg/kg urapidil administration 3 minutes before induction of anaesthesia, 7 mg/kg thiopentone and 1 µg/kg fentanyl were given and endotracheal intubation was performed by 0.1 mg/kg pancuronium. Anaesthesia was maintained with 50% nitrous oxide-oxygen in approximately 1% isoflurane. Same dose urapidil was administered 3 minutes before sternotomy as well. Heart rate, mean arterial and central venous pressures were recorded; 1- three minutes before induction of anaesthesia, prior to urapidil administration (endotracheal intubation), 2- immediately after intubation, 3- 4- 5- one, three and five minutes after intubation, 6- three minutes before sternotomy, 7- 8- 9- one, three and five minutes after sternotomy. There was no statistically significant difference in heart rate and mean arterial pressures among different measurement intervals.
In conclusion, we succeeded to provide haemodynamic stability till cardiopulmonary bypass by administering i.v. bolus urapidil before induction of anaesthesia and sternotomy.Keywords: Anaesthesia, Blood pressure, UrapidilTurkiye Klinikleri J Med Sci 1999, 19:1-5
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