ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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ORIGINAL RESEARCH ARTICLES |
Intraarterial Chemotherapy For Primary Irresectableliver Tumors
Erol Eroğlu*, Recep Çetİn**, Hakan Bulak***, Mustafa KalaycI***, Süleyman Oral****
* Uzm.Dr., Süleyman Demirel Üniversitesi Tıp Fakültesi Cerrahi Onkoloji BD, Arş.Gör.,
** Yard.Doç.Dr., Süleyman Demirel Üniversitesi Tıp Fakültesi Cerrahi Onkoloji BD, ISPARTA
*** Uz.Dr., Ankara Onkoloji Hastanesi III. Cerrahi Kliniği,
**** Uz.Dr., Ankara Onkoloji Hastanesi III. Cerrahi Kliniği, Klinik Şefi, ANKARA
Patients with primary liver tumors (hepatocellular carcinoma) who had been applied intraarterial catheterization and intraarterial chemotherapy between 1991-1997 were analyzed retrospectively. There were 7 female and 8 male patients. 15 patients were catheterized, but 12 of them could be evaluated for response. Two patients died in the postoperative period and 1 patient was out of follow-up. According to the percent of hepatic replacement of tumors 3 patients were evaluated as stage I, and 12 patients as stage II. Six of the catheterized patients received 5 Fluorouracil + Ca Folinate, and 6 patients received 5 Fluorouracil + Mitomycin C. Complications were detected in 5 (33.3%) patients, and toxic effects were seen in 41.6% of patients. From 12 patients who received intraarterial chemotherapy, 2 of them responded to therapy. Overall response rate was 16.6%, and the median survival was 13 months. These results were found to be similar with systemic chemotherapy. In conclusion, intraarterial chemotherapy for primary irresectable liver tumors was not effective as expected, and has a high complication rate.Keywords: Liver, Tumor, Intraarterial,
ChemotherapyTurkiye Klinikleri J Med Sci 1999, 19:255-258
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