ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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ORIGINAL RESEARCH ARTICLES |
The Effect Of Vitamin C On Erythrocyte Superoxide Dismutase Activity And Lipid Peroxidation Levels Of Skiers Training At Mid-altitude
Hale SAYAN*, Ebru ÇETİN**, İmdat YARIM**, Bilge GÖNÜL***
* Araş.Gör.Dr., Gazi Üniversitesi Tıp Fakültesi Fizyoloji AD,
** Araş.Gör.Dr., Gazi Üniversitesi Beden Eğitimi ve Spor Yüksekokulu,
*** Prof.Dr., Gazi Üniversitesi Tıp Fakültesi Fizyoloji AD, ANKARA
Exposure to high-altitude is known that some acclimatization mechanism work for adaptation of hypobaric hypoxemic condition. Recently, some studies have shown that exposure to high-altitude may influence free radical generation. It is reported that a decreased filterability of erythrocyte at high altitude may be due to an increased lipid peroxidation of membrane lipids.
This study was performed on 7 male and 7 female cross-country skiers of Gazi University School of Physical Education and Sports. The aim of this study was to investigate the effect of vitamin C supplementation on erythrocyte lipid peroxidation and SOD enzyme activity in the aclimatization period of 1800 m. They prepared themselves individually training program at 1800 m for 5 days. During the mid-altitude period , we studied the effects of vitamin C supplementation on erythrocyte MDA, SOD enzyme activity, plasma vitamin C and VO2max as an indicator of the aerobic power. 7 subjects were supplemented by vitamin C (1000mg/day) for 5 days, the other 7 subjects are considered as control and they did not receive vitamin C supplementation. All blood samplings were performed before and at the end 5th day of the mid-altitude period.
The MDA levels of the vitamin C supplemented group were decreased and the SOD enzyme activity were significantly increased compared to control group and initial levels.
In conclusion, we suggest that vitamin C supplementation may support the decrease in lipid peroxidation of skiers, training at mid-altitude.Keywords: mid-altitude, vitamin C, erythrocyteTurkiye Klinikleri J Med Sci 2000, 20:5-10
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