ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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Rejection Encephalopathy
Nimet KABAKUŞ*
*Yrd.Doç.Dr., Fırat Üniversitesi Tıp Fakültesi Pediatri AD, ELAZIĞ
Successful organ transplantation leads to rapid resolution of many of the features of chronic organ failure, but may itself be complicated by neurological disturbances. Rejection encephalopathy (RE) is one of these disturbances. RE is a syndrome which occurs after major organ transplantation such as bone marrow, kidney, liver, and during acute rejection crises. The encephalopathy which is not due to electrolyte disturbance, hypertension, drug/radiotherapy or fever, occurs in this syndrome. RE is characterized by convulsions, headache, and confusion with reversible electroencephalographic changes. Occasionally, progressive multifocal leukoencephalopathy, central pontine myelinolysis, and spongioform encephalopathy have occured during the fulminant course of rejection crises. Differential diagnosis should be made especially because of intracranial disorders. The definition of the syndrome of rejection encephalopathy and its relation to the severity of the rejection has important therapeutic implications. Steroid therapy should not be withdrawn or reduced because acute neurological features. Although the severe neurological features associated with RE, long-term follow-up has not revealed any late sequel.Keywords: Rejection, encephalopathyTurkiye Klinikleri J Med Sci 2000, 20:17-19
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