ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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ORIGINAL RESEARCH ARTICLES |
Flow Cytometric And Light Microscopic Investigationof Human Fetal Liver
Sevim AYDIN*, Yavuz TEKELİOĞLU**, Ersan ODACI*, Ayşe ARVAS***, Haluk ARVAS**
* Uz.Dr., Karadeniz Teknik Üniversitesi Tıp Fakültesi Histoloji ve Embriyoloji AD,
** Yrd.Doç.Dr., Karadeniz Teknik Üniversitesi Tıp Fakültesi Histoloji ve Embriyoloji AD,
*** Dr., Karadeniz Teknik Üniversitesi Tıp Fakültesi Histoloji ve Embriyoloji AD, Öğretim Görevlisi,
**** Prof.Dr., Karadeniz Teknik Üniversitesi Tıp Fakültesi Histoloji ve Embriyoloji AD, TRABZON
In our study, it was aimed to investigate the development of fetal liver by classic light microscopy and flow cytometry analysis and also compare with adult liver with respect to morphologic and physiological properties. In the fetus, aged between 18 and 29 weeks, it was observed that by light microscopy that the liver cell cords are not formed yet and the irreguler hepatocyte design was also observed. S and G2/ M phases values in this group were observed higher than the fetus aged between 30 and 39 weeks by flow cytometric analysis because of the increased hemopoietic activitiy. In the fetus aged between 30 and 39 week, it was observed that the liver cell cords are becoming to convert the shape of the adult liver cords. Because of the dec-reased hemopoietic activity, S and G2/ M phases values in this group were observed lower than that of the fetus aged between 18 and 29 week. In conclusion, because of the increased mitotic activity in the fetus aged between 18 and 29 weeks, the histologic structure of the liver is different from the histologic structure of the adult liver. However, the histologic structure of the liver in the fetus aged between 30 and 39 weeks start to convert the histological structure of the liver.Keywords: Fetus, liver, light microscopy,
flow cytometryTurkiye Klinikleri J Med Sci 2000, 20:57-65
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