ISSN: 1300-0292 İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED CINAHL, Index Copernicus, Chemical Abstracts (CA), Excerpta Medica / EMBASE Dil: Türkçe, İngilizce İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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Leptins
Kanat GÜLLE*, Erdal KARAÖZ**
* Biyolog, Süleyman Demirel Üniversitesi Tıp Fakültesi Histoloji - Embriyoloji AD,** Doç.Dr., Süleyman Demirel Üniversitesi Tıp Fakültesi Histoloji - Embriyoloji AD, ISPARTA Leptin, a 16-kDa peptid that circulates in plasma, is a part of a feedback loop that regulates fat mass by decreasing food intake and increasing energy expenditure. Leptin is secreted by adipocytes, placenta, and stomach. Circulating levels of it is influenced by the degree of adiposity, gender, acute changes in energy balance (independent of changes in adiposity), and various hormones, such as insulin and glucocorticoids. In this article we have reviewed the latest information about leptin, including the structure, functions, receptors, and relationship with obesity.Keywords: Leptin, Structure, Obesity, ExpressionTurkiye Klinikleri J Med Sci 2000, 20:112-121
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