05-07-2008

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İstatistik ve Epidemiyoloji Danışmanları
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Tıp Bilimleri Dergisi
ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri

 

ORIGINAL RESEARCH ARTICLES


Evaluation Of Trauma Scores, And At-iii, Blood Trombocyte Count, Aptt And Pt In Patients With Multiple Trauma Admitted To Emergency Service

Yusuf YAĞMUR*, Mustafa UĞUR**, İsmail Hamdi KARA***,
Cafer GÜLOĞLU**, Mustafa ALDEMİR****, Mehmet KİRAZ*****

* Doç.Dr., Dicle Üniversitesi Tıp Fakültesi Genel Cerrahi AD,
** Uz.Dr., Dicle Üniversitesi Tıp Fakültesi İlk ve Acil Yardım AD,
*** Yrd.Doç.Dr., Dicle Üniversitesi Tıp Fakültesi Aile Hekimliği AD,
**** Uz.Dr., Dicle Üniversitesi Tıp Fakültesi Genel Cerrahi AD,
***** Uz.Dr., Dicle Üniversitesi Tıp Fakültesi Aile Hekimliği AD, DİYARBAKIR



In this prospective study, we aimed to show how trauma severity and posttraumatic time effect some blood parameters such as anti-thrombin III (AT-III), blood trombocyte count, active partial thromboplastin time (aPTT), prothrombin time (PT), and fibrinogen level.
Thirty patients with multiple trauma admitted to Dicle University Hospital, Department of Emergency between January 1998-March 1999 were evaluated. Bloods for tests would be based to evaluation were taken intravenously from all patients at admission and third posttraumatic days for evaluating parameters. Patients were divided into three groups according to Injury Severity Score (ISS) and Glasgow Coma Score (GCS): Group I- patients (n=8) with severe multiple trauma and severe head trauma (ISS>25, GCS<8); Group II- patients (n=8) with severe trauma and mild head trauma (ISS >25, GCS>12); Group III- patients (n=14) with mild multiple trauma and mild head trauma (ISS <25, GCS>12). Statistical analysis was done with SPSS 6.0 software.
Anti-thrombin III level was lower in Group II (high ISS) when compared to Group I and III (p=0.007). Although AT-III level in Group II was little but increased at 3rd day, it was still lower than Group I and III. Anti-thrombin levels of groups at admission and 3rd days were as follows: 32.3±11.5 mg/dl and 35±27.9 in Group I; 26.7± 8.1 mg/dl, 30.8± 11.8 mg/dl in Group II; 39.7± 8.9 mg/dl, 39.3±14.6 mg/dl in Group III. No statistical significance was found in aPTT, thrombocyte counts of groups (p>0.05). Prothrombin time was decreased at 3rd day when all patients were examined (p=0.0006). Although fibrinogen were in the normal levels in all groups, in Group II it was higher at admission when compared to other groups (p=0.02), however, no significance was found at 3rd day (p>0.05).As a conclusion, the risk of thromboembolism phenomena increases in patients with multi-trauma who admitted to Emergency Service, and it was considered that therapy would be planned according to this condition.


Keywords: Antithrombin III, Multiple trauma, Trauma score

Turkiye Klinikleri J Med Sci 2000, 20:123-131

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