ISSN: 1300-0292 İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED CINAHL, Index Copernicus, Chemical Abstracts (CA), Excerpta Medica / EMBASE Dil: Türkçe, İngilizce İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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ORIGINAL RESEARCH ARTICLES |
Morphometric And Ultrastructural Studyof Human Fallopian Tube Epithelium
V. Sevinç İnan*, H. Seda Vatansever**, M. Kemal Özbİlgİn**,Mine Yurtseven***, Mürvet Tuncel****
* Uz.Dr., Celal Bayar Üniversitesi Tıp Fakültesi, Histoloji - Embriyoloji AD,** Yrd.Doç.Dr., Celal Bayar Üniversitesi Tıp Fakültesi, Histoloji - Embriyoloji AD, MANİSA*** Prof.Dr., Ege Üniversitesi Tıp Fakültesi, Histoloji-Embriyoloji AD, İZMİR**** Doç.Dr., Hacettepe Üniversitesi Tıp Fakültesi, Anatomi AD, ANKARA The fallopian tube is the site of gamete transport, fertilization, and early embryo development. Epithelium of the fallopian tube is known significant morphological variations in response to changes in estrogen and progesterone concentrations. The aim of this study is to compare morphometric and ultrastructural changes in isthmic portion of human fallopian tube epithelium at different stages of the menstrual cycle and early pregnancy.
Fifteen healthy women undergoing tubal ligation were included in this study. During the menstrual cycle the epithelial height and volume were observed on serial sections and were calculated by stereological technique.
While the height of ciliated cells was increased during the proliferative phase, maximal ciliation was attained around the time of ovulation. Also, deciliation and the decrease of epithelial height were observed after ovulation and early pregnancy. By electron microscopic examination, secretory cells were seen to have more marked ultrastructural changes than ciliated cells during the cycle.
The evidence suggests that the epithelium of the fallopian tube had morphological changes that consist of changes in both epithelial volume and cell population during the menstrual cycle and early pregnancy. Because these differences especially were observed with ovulation, the fallopian tube may play a crucial role during fertilization and early development of embryo.Keywords: Fallopian tube, morphometry, ultrastructureTurkiye Klinikleri J Med Sci 2000, 20:347-355
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