ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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Comparison Of Diabetes And Impaired Glucose Metabolismdiagnosis According To World Health Organisation Andamerican Diabetes Association Diagnostic Criteria
Serpil Salman*, Fatih Salman*, Selda Gedİk*, İrfan Baştar**, Yücel YIlmaz*,
Sevda Özel Çİftcİ***, Kubilay KarşIdağ**, Nevin Dİnççağ**, İlhan Satman**,
M. Temel YIlmaz**
* İstanbul Üniversitesi Deneysel Tıp Araştırma Enstitüsü, Metabolizma ve Diyabet Araştırma ve Uygulama Birimi,
** İstanbul Üniversitesi İstanbul Tıp Fakültesi, İç Hastalıkları AD, Diyabet BD,
*** İstanbul Üniversitesi İstanbul Tıp Fakültesi, Halk Sağlığı AD, Biyoistatistik ve Demografi BD, İSTANBUL
American Diabetes Association (ADA) Experts Committee recommended in 1997 a new criterion about diabetes classification as an alternative to Oral Glucose Tolerance Test (OGTT) suggested by World Health Organization (WHO). For this new classification, the measurement of fasting glucose level is used for diagnosis of diabetes.
This study objective was to compare ADA and WHO criterion by reclassification of 1767 OGTT tests. For this aim, the plasma glucose level at the beginning of OGTT was classified based on ADA criterion and these results compared to 2nd hour plasma glucose levels.
In the whole study group, 81.89% (n:1447) of the sample was normal either by ADA or WHO criteria. Additionally 1.75% (n:31) was Impaired Fasting Glucose (IFG) and 3.68% (n:60) was Impaired Glucose Tolerance (IGT). Most of the people (85.51%, n:1511) were in the corresponding group by the both classification. When the diabetic patients by WHO criteria (n:65) were reclassified by ADA criteria, 50.77% (n:33) were diabetic and 21.54% (n:14) had IFG. Most of the proportion whose diagnosis was IGT by WHO criteria were normal based on ADA categorization (76.68%, n:148). 53.51% (n:52) of IFG diagnosed individuals, 2nd hour blood glucose levels were in the normal range by WHO classification.
OGTT is the gold standard for diabetes diagnosis. If a new diagnostic criterion is chosen, it must be more accurate and reliable. We conclude that ADA criterion is insufficient for the diagnosis of IGT group. IGT is an important part of diabetes classification, so its predictive value is known about cardiovascular morbidity and mortality. On the other hand there is not an equivalent definition in ADA classification. Some widerpulation studies. Additionally practicality, low costs and speed are the advantages of ADA classification for such studies. But to decide a personal diagnosis, WHO classification is preferable.Keywords: Diabetes mellitus, Type 2, Blood Glucose, Glucose Tolerance TestTurkiye Klinikleri J Med Sci 2001, 21:63-68
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