ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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Case Report-the Effects Of Calcium Channel Blockerson Platelet Function
Fatma YÜCEL BEYAZTAŞ*, Süleyman Murat ASLAN**, Berrin Dilek ASLAN***
* Yrd.Doç.Dr., Cumhuriyet Üniversitesi Tıp Fakültesi Adli Tıp AD,
** Yrd.Doç.Dr., Cumhuriyet Üniversitesi Tıp Fakültesi Kardiyoloji AD,
*** Yrd.Doç.Dr., Cumhuriyet Üniversitesi Tıp Fakültesi Anesteziyoloji ve Reanimasyon AD, SİVAS
Purpose: It is known that calcium channel blockers have antiplatelet effects. As deaths from this mechanism is rare, exitus because of bleeding with high dose verapamil was searched and literature was examined.
Materials and Methods: The case, which committed a suicide with high dose calcium channel blocker; verapamil, was examined by clinical observation and forensic autopsy in Cumhuriyet University Hospital.
Results: In the clinical observations of the case having taken high dose verapamil, there was decrease of thrombocyte number and elevation of prothrombin and activated partial thromboplastin times. There was no pathological findings that could explain cause of death except, excessive clotted blood intraabdominaly in the forensic autopsy.
Conclusion: As there was no additional supporter disease which could cause bleeding, verapamil's antiplatelet effects were thought as the cause of the bleeding. It was concluded that, while using these drugs, the antiplatelet effects of them must be remembered.Keywords: Calcium Calcium Channel Blockers, Platelet function, Verapamil, Platelet Aggregation, Forensic medicineTurkiye Klinikleri J Med Sci 2001, 21:121-123
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