ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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ORIGINAL RESEARCH ARTICLES |
Inspection Of The Maturation-fertilization Andcleavage Relationship Of The Oocytes In Different Phases
Mehmet CINCIK*, Şaban SEZEN**, Tansu KÜÇÜK***
* Yrd.Doç.Dr., GATA, Tıbbi Histoloji ve Embriyoloji AD,
** Uz.Dr., GATA, Tıbbi Histoloji ve Embriyoloji AD,
The big part of the unsuccessful rate at IVF is composed of oocyt immaturity. These must pass through IVM phase. In this study, it is aimed to explain the abilities of in-vitro maturation, fertilization and cleavage of oocytes by discussing the relationship between them.
Total 761 oocytes (150 immature, 176 intermediate, 435 mature) picked up by performing follicle aspiration from the 32 patients who applied to GATA IVF center in different periods were inspected. While the fertilization rate is 92% on inseminated mature oocytes at the end of a six hour incubation period, for IVM on the immature oocytes groups incubated 6-48 hours, this rate was found 48% on prophase I (PI), 74% on metaphase I (MI). The rate of cleavage of fertilized oocytes was found 84% on mature oocytes (MII), while it was seen 34% on PI oocytes and 62.5% on MI oocytes.
As a result, the more maturation proceeds the more fertilization ability increases. Oocytes on MII phase are the ones, which have the most fertilization ability.Keywords: Oocytes, Sperm Maturation, fertilizationTurkiye Klinikleri J Med Sci 2001, 21:77-82
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